Epigenome Successes in ERC "Advanced Grants"

The European Research Council has selected projects headed by four lab leader members of the Epigenome NoE: Geneviève Almouzni, Wendy Bickmore, Ueli Grossniklaus and Edith Heard. We all heartily congratulate Geneviève, Wendy and Edith (all working in the same Epigenome research work package Assembly and Nuclear Organisation), and Ueli and wish them every success with their new projects. more . .

---

Epigenome's Newest Protocol A Guideline for ChIP - Chip Data Quality Control and Normalization

ChIP-on-chip is a powerful technique to measure genome-wide binding sites for proteins of interest. Despite having become very popular during the last 5 or so years, the data analysis is far from being standardized, and many different combinations of methods are being applied. This guideline attempts to give an orientation in the multitude of data transformation and normalization methods employed, by giving clear recommendations for or against using various procedures or by suggesting improvements.

---