Positions for new and existing research teams
- Centre for Epigenetics & Cell Fate, l’Université Paris, Paris, France

Description: A centre for Epigenetics and Cell Fate will be created in 2008 at the new Tolbiac campus of l’Université Paris 7, Paris Rive Gauche (75020 Paris cedex 13). This project will be supported by the three organizations: CNRS, Inserm and Université Paris 7. The research focus will be on the epigenetic modifications that regulate cell fate involving diverse model organisms and will include a human embryonic stem cell component.

The research groups within the centre will have access to the technical platforms of the IFR Biologie Systémique/Institut Jacques Monod as well as additional core facilities for functional genomics. The future centre is seeking new epigenetics research teams that are either established or in the process of being formed. The prospective teams should have strong background in the general area of epigenetics and cell fate. Specific research themes could include, but are not limited to, epigenetic mechanisms that regulate development and differentiation. The use of all model organisms will be considered and the only criterion for selection will be the scientific merit of the project and the investigators.

Application Details: Applicants should submit their curriculum vitae and a description of their research project (not exceeding 30,000 characters in length). Applications should be submitted electronically in pdf format by October 16, 2006 to [email protected] and [email protected]. The application should be accompanied by two letters of recommendation. Candidates will be selected on the basis of this initial application procedure will be invited to present a seminar before a selection committee between September 21 and 26, 2006. The results of the search will be communicated from September 28, 2006.

Contacts:
Marc Lalande
Department of Genetics and Developmental Biology
University of Connecticut Health Center
263 Farmington Avenue
Farmington, CT 06030-3301
Tel: (860) 679-8349

Evani Viegas-Pequignot
Epigénétique, Pathologies et Développement
U 741 Inserm/P7
Tour 43/2ème étage/couloir 43-44
2, Place Jussieu
75251 Paris cedex 05
tel. 33 (0) 1 44 27 28 15
fax. 33 (0) 1 44 27 82 10

Closing Date: 2006-10-16

Research
- Max-Planck Institute of Immunobiology, Freiburg, Germany

Description: Laboratory Rudolf Grosschedl seeks highly motivated and skilled individuals to join a research team working on signaling-dependent transcription control of lymphocyte differentiation and the mechanisms by which higher-order chromatin structure regulates gene expression.

The MPI of Immunobiology offers a highly interactive and international research environment with state-of-the-art core facilities.

Qualifications: Candidates should have an excellent track record and experience in standard molecular and cell biology techniques, biochemisty, or 3D-FISH and cell imaging. In addition, applications of individuals with experience in mouse development are welcome.

Salary Details: Remuneration is commensurate with experience.

Application Details: Please send your application with full supporting documentation to Rudolf Grosschedl laboratory or to:

Max-Planck Institute of Immunobiology
Nele Leibrock
Stuebeweg 51
D-79108 Freiburg
Germany

Closing Date: Check with institute

Post-doctoral position in epigenetic mechanisms of cellular memory
- University of Heidelberg, Heidelberg, Germany

Description: We use Drosophila melanogaster as a model organism to study how gene expression patterns are faithfully and heritably maintained in cell lineages. A postdoctoral position is available to study the genome-wide regulatory role of Polycomb and Trithorax proteins in maintaining such transcriptional expression states. The project utilizes the ChIP-on-Chip technology to map epigenetic marks at genes regulated by Polycomb/Trithorax proteins.

The position (starting date January 2006 or later) is funded through a chromatin network established between research institutions in Heidelberg and Munich (SFB/Transregio 5).

Application Details: Interested candidates should send their CV and names of three referees to:

Prof. Renato Paro
ZMBH
University of Heidelberg
INF 282
69120 Heidelberg
Germany

Closing Date: Check with institute

Post-doctoral position
- Centre for Addiction and Mental Health and the University of Toronto, Toronto, Canada

Description: NIH and CIHR supported positions for post-doctoral fellows are available immediately at the Krembil Family Epigenetics Laboratory of the Centre for Addiction and Mental Health, and University of Toronto, for qualified candidates to study epigenomics of schizophrenia, major depression, and other complex diseases using high throughput technologies such as microarrays. Highly motivated individuals with a record of productivity and ability to work well with others are encouraged to apply.

Qualifications: A strong background in molecular biology is required. Experience in epigenetic research is desirable but not mandatory.

Salary Details: Starting salary $50K Cdn

Application Details: Applicants should submit a summary of their research experience, Curriculum Vitae, and the names of several referees to:

Dr. Art Petronis
The Krembil Family Epigenetics Laboratory
Centre for Addiction and Mental Health
University of Toronto
250 College Street
Toronto ON M5T 1R8
Canada

Closing Date: Check with institute

Post-doctoral position: Visualising transcription in living cells
- Wellcome Trust Biocentre, University of Dundee, Dundee, UK

Description: We have developed a novel method to directly watch the transcription of a gene in living cells (Current Biology 16:1018-25). We found "pulses" of transcription, with the gene turning on and off at irregular intervals. This is a highly powerful new method for analysing gene regulation. The proposed project will expand this technology to look at new genes in different contexts and to explore the regulation of transcriptional pulsing.

The position is funded by the MRC and will initially be for 3 years.

Qualifications: Experience with molecular biology is essential.

Application Details: If interested, please contact the supervisor, Dr. Jonathan Chubb, directly and include a CV with the names of 3 referees.

Closing Date: Check with institute

Post-doctoral position: Modulation of chromatin higher order structure
- MRC Laboratory of Molecular Biology, Cambridge, UK

Description: The Group of Daniela Rhodes seeks a highly motivated and enthusiastic post-doctoral researcher to join a research team working on the structure of the "30nm" chromatin fibre (see PNAS 103: 6506 (2006)). The individual is expected to lead a project aimed at understanding how post-transcriptional modification of the histone octamer tails and the linker histone, modulate higher order chromatin structure folding and dynamics.

The MRC Laboratory of Molecular Biology offers a highly interactive and international research environment with state-of-the-art core facilities.

Qualifications: Candidates should have a background in biochemistry and biophysical techniques such as electron microscopy. Applications from individuals with experience in chromatin biology are welcome.

Salary Details: The position is available immediately (September 2006) and salary will be determined by the candidate's experience.

Application Details: Interested candidates should send their CV and names of three referees to:

Dr Daniela Rhodes
MRC-Laboratory of Molecular Biology
Hills Road
Cambridge
CB2 2QH
UK

Tel: +44 1223 402441
Fax: +44 1223 213556

Closing Date: Check with institute

Postdoctoral scientist position in epigenetics/immunology/cancer
- NYU Medical School, New York, New York, USA

Description: A postdoctoral position is available immediately in the laboratory of Dr. Jane Skok at the Department of Pathology, NYU Medical School in New York to work on a project examining the events that lead up to malignant transformation of developing B cells in pro- and pre-B acute lymphoblastic leukaemia (ALL). The aim of the project is to test the hypothesis that nuclear organization is an important factor determining the developmental timing of both initiating and secondary events which ultimately lead to leukaemic transformation of cells during early B cell development.

Qualifications: Interested candidates should have a PhD in immunology, molecular biology, genetics or related fields. This position requires lab techniques including, but not limited to 3-D DNA FISH, confocal microscopy, molecular biology, bioinformatics, cell culture, FACS analysis and chromatin immunoprecipitation. Candidates should be highly motivated, creative and capable of contributing productively as part of a team. The laboratory is located in the Medical School Building of the NYU Medical Center which is in mid-town Manhattan.

Salary Details: Salary and benefits will be commensurate with experience.

Application Details: Interested applicants should forward a cover letter, current and future research interests, curriculum vitae, list of publications and the names, telephone numbers and e-mail addresses of three references by e-mail to:

Jane Skok, Ph. D.
Assistant Professor
Dept of Pathology NYU-SOM
550 First Ave, MSB 531
New York, NY 10016
USA

Tel Office: +001 (212) 263 0504

Closing Date: Check with institute